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Merck

PRKCE

protein kinase C, epsilon

Sinónimos:
PKCE, nPKC-epsilon
Especie:
ID UniProtKB:
ID del gen:
  • Human(5581) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
  • Mouse(18754) protein kinase C, epsilon
  • Rat(29340) protein kinase C, epsilon
  • chicken(421409) protein kinase C, epsilon
  • domestic cat(101100958) protein kinase C, epsilon
  • dog(609934) protein kinase C, epsilon
  • cow(507041) protein kinase C, epsilon
  • Horse(100053394) protein kinase C, epsilon
  • Domestic Rabbit(100009103) protein kinase C, epsilon
  • sheep(101110314) protein kinase C, epsilon
  • naked mole-rat(101700837) protein kinase C, epsilon
  • domestic guinea pig(100721814) protein kinase C, epsilon

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Ácido oleico, ≥99% (GC),
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-PKC ε antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-PKC epsilon Antibody, clone 8I8K4, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
H-7 dihydrochloride, ≥98% (HPLC),
Especie
human
Ácido oleico, ≥99% (GC),
Especie
human
UCN-01, ≥97% (HPLC), powder,
Especie
human
GSK690693, ≥98% (HPLC),
Especie
human

Proteins

Referencia del producto
Descripción
Especie
PKC ε , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Prkce,
Especie
mouse
MISSION® esiRNA, targeting human PRKCE,
Especie
human