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Merck

POLD2

polymerase (DNA directed), delta 2, accessory subunit

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(5425) Summary: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
  • Mouse(18972) polymerase (DNA directed), delta 2, regulatory subunit
  • Rat(289758) polymerase (DNA directed), delta 2, accessory subunit
  • domestic cat(101095089) polymerase (DNA directed), delta 2, accessory subunit
  • dog(482686) polymerase (DNA directed), delta 2, accessory subunit
  • cow(281991) polymerase (DNA directed), delta 2, regulatory subunit 50kDa
  • sheep(101117838) polymerase (DNA directed), delta 2, accessory subunit
  • Domestic Rabbit(100358263) polymerase (DNA directed), delta 2, accessory subunit
  • domestic guinea pig(100727561) polymerase (DNA directed), delta 2, accessory subunit
  • naked mole-rat(101722261) polymerase (DNA directed), delta 2, accessory subunit
  • chicken(100859398) polymerase (DNA directed), delta 2, accessory subunit
  • Thale Cress(818812) DNA polymerase delta subunit 2
  • Zebrafish(796456) polymerase (DNA directed), delta 2, regulatory subunit

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DNA polymerase δ p50 antibody, Rat monoclonal, clone PDK 7B4, purified from hybridoma cell culture,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-POLD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Cytosine β-D-arabinofuranoside hydrochloride, crystalline,
Especie
human
Cytarabine, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Cytarabine, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Cytarabine, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Cytarabine, British Pharmacopoeia (BP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human POLD2,
Especie
human
MISSION® esiRNA, targeting mouse Pold2,
Especie
mouse