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Merck

PLCG1

phospholipase C, gamma 1

Sinónimos:
NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
Especie:
ID UniProtKB:
ID del gen:
  • Human(5335) Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18803) phospholipase C, gamma 1
  • Rat(25738) phospholipase C, gamma 1
  • naked mole-rat(101705192) phospholipase C, gamma 1
  • chicken(419175) phospholipase C, gamma 1
  • dog(485874) phospholipase C, gamma 1
  • Zebrafish(373867) phospholipase C, gamma 1
  • domestic cat(101092925) phospholipase C, gamma 1
  • cow(281987) phospholipase C, gamma 1
  • domestic guinea pig(100716986) phospholipase C, gamma 1
  • sheep(101103341) phospholipase C, gamma 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Phospho-PLC gamma 1 (PLCG1)-Y783 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-PLCG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-PLCG1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
Anti-phospho-PLCG1 (pTyr783) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-PLCG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PLCG1,
Especie
human
MISSION® esiRNA, targeting mouse Plcg1,
Especie
mouse