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Merck

PIAS2

protein inhibitor of activated STAT, 2

Sinónimos:
ARIP3, DIP, MIZ, MIZ1, PIASX, PIASX-ALPHA, PIASX-BETA, SIZ2, ZMIZ4
Especie:
ID UniProtKB:
ID del gen:
  • Human(9063) Summary: This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]
  • Mouse(17344) protein inhibitor of activated STAT 2
  • Rat(83422) protein inhibitor of activated STAT, 2
  • Zebrafish(564149) protein inhibitor of activated STAT, 2
  • domestic guinea pig(100718605) protein inhibitor of activated STAT, 2
  • naked mole-rat(101709303) protein inhibitor of activated STAT, 2
  • sheep(101112782) protein inhibitor of activated STAT, 2
  • cow(533403) protein inhibitor of activated STAT, 2
  • Horse(100068879) protein inhibitor of activated STAT, 2
  • domestic cat(101081835) protein inhibitor of activated STAT, 2
  • dog(480147) protein inhibitor of activated STAT, 2
  • chicken(416383) protein inhibitor of activated STAT, 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Pias2 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-PIAS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-PIAS2 Antibody, clone 4I6K6, Rabbit Monoclonal, ,
Reactividad de especies
mouse, rat
Aplicación
western blot
Anti-PIAS1+PIAS2 Antibody, clone 8P1D2, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PIAS2,
Especie
human
MISSION® esiRNA, targeting mouse Pias2,
Especie
mouse