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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

Sinónimos:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
Especie:
Human PDE1A (5136), Mouse Pde1a (18573), Rat Pde1a (81529), chicken PDE1A (424116), Zebrafish pde1a (564465), domestic cat PDE1A (101083101), dog PDE1A (403652), naked mole-rat Pde1a (101712147), sheep PDE1A (101119369), Domestic Rabbit PDE1A (100346878) ...Más
ID UniProtKB:
P54750, D3DPG5, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2
ID del gen:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA022151
Anti-PDE1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
M2547
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
Especie
human
V6383
Vinpocetine, ≥98%, solid,
Especie
human
1220506
Dipyridamole, United States Pharmacopeia (USP) Reference Standard,
Especie
human
BP1102
Dipyridamole impurity standard, British Pharmacopoeia (BP) Reference Standard,
Especie
human
BP131
Dipyridamole, British Pharmacopoeia (BP) Reference Standard,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
SRP0257
PDE1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Especie
human
SRP5339
PDE1A, active, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU074801
MISSION® esiRNA, targeting human PDE1A,
Especie
human
EMU077501
MISSION® esiRNA, targeting mouse Pde1a,
Especie
mouse