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Merck

PCDHAC2

protocadherin alpha subfamily C, 2

Sinónimos:
PCDH-ALPHA-C2
Especie:
ID UniProtKB:
ID del gen:
  • Human(56134) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  • Mouse(353237) protocadherin alpha subfamily C, 2
  • Rat(393092) protocadherin alpha subfamily C, 2
  • Horse(100146554) protocadherin alpha subfamily C, 2
  • dog(478037) protocadherin alpha subfamily C, 2
  • chicken(497224) protocadherin alpha subfamily C, 2
  • Zebrafish(100535313) protocadherin alpha subfamily C, 2
  • Domestic Rabbit(100352395) protocadherin alpha subfamily C, 2
  • domestic cat(101098920) protocadherin alpha subfamily C, 2
  • naked mole-rat(101703754) protocadherin alpha subfamily C, 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PCDHAC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence