PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
Sinónimos:
AR-JP, LPRS2, PDJ, PRKN
Especie:
Human PARK2 (5071), Mouse Park2 (50873), Rat Park2 (56816), cow PARK2 (530858), naked mole-rat Park2 (101700770), domestic guinea pig Park2 (100724550), Horse PARK2 (100057832), Zebrafish park2 (550328), chicken PARK2 (421577), dog PARK2 (612316) ...Más
ID UniProtKB:
ID del gen:
- Human(5071) Summary: The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
- Mouse(50873) Parkinson disease (autosomal recessive, juvenile) 2, parkin
- Rat(56816) parkinson protein 2, E3 ubiquitin protein ligase
- cow(530858) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- naked mole-rat(101700770) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- domestic guinea pig(100724550) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- Horse(100057832) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- Zebrafish(550328) Parkinson disease (autosomal recessive, juvenile) 2, parkin
- chicken(421577) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- dog(612316) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- domestic cat(101098228) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- sheep(101113503) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Parkin antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PARK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Parkin antibody, Mouse monoclonal, clone PRK8, purified from hybridoma cell culture,
Reactividad de especies
hamster, human, mouse, rat
Aplicación
microarray
western blot
western blot
esiRNA
Referencia del producto
Descripción
Especie