OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
Sinónimos:
IFI-4, OIAS, OIASI
Especie:
Human OAS1 (4938), Horse OAS1 (100034147), dog OAS1 (608778), domestic guinea pig Oas1 (100721851), naked mole-rat Oas1 (101699903), domestic cat OAS1 (101087875), sheep OAS1 (100294650), sheep OAS1 (101110181)
ID UniProtKB:
ID del gen:
- Human(4938) Summary: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
- Horse(100034147) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
- dog(608778) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
- domestic guinea pig(100721851) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
- naked mole-rat(101699903) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
- domestic cat(101087875) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
- sheep(100294650) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
- sheep(101110181) 2'-5'-oligoadenylate synthetase 1, 40/46kDa
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-OAS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-OAS1 Antibody, clone 1N2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot