Saltar al contenido
Merck

NLRP10

NLR family, pyrin domain containing 10

Sinónimos:
CLR11.1, NALP10, NOD8, PAN5, PYNOD
Especie:
ID UniProtKB:
ID del gen:
  • Human(338322) Summary: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(244202) NLR family, pyrin domain containing 10
  • Rat(293426) NLR family, pyrin domain containing 10
  • dog(611323) NLR family, pyrin domain containing 10
  • Horse(100070865) NLR family, pyrin domain containing 10
  • domestic cat(101089644) NLR family, pyrin domain containing 10
  • naked mole-rat(101702326) NLR family, pyrin domain containing 10

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-NLRP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-NLRP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-NALP10 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

Referencia del producto
Descripción
Especie
PrEST Antigen NLRP10, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Especie
human
PrEST Antigen NLRP10, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human NLRP10,
Especie
human
MISSION® esiRNA, targeting mouse Nlrp10,
Especie
mouse