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Merck

MCM2

minichromosome maintenance complex component 2

Sinónimos:
BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
Especie:
ID UniProtKB:
ID del gen:
  • Human(4171) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
  • Mouse(17216) minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
  • Rat(312538) minichromosome maintenance complex component 2
  • fruit fly(40973) Minichromosome maintenance 2
  • Thale Cress(841056) minichromosome maintenance protein 2
  • domestic guinea pig(100722936) minichromosome maintenance complex component 2
  • naked mole-rat(101710978) minichromosome maintenance complex component 2
  • sheep(101116097) minichromosome maintenance complex component 2
  • cow(510120) minichromosome maintenance complex component 2
  • domestic cat(101090176) minichromosome maintenance complex component 2
  • dog(484622) minichromosome maintenance complex component 2
  • chicken(416027) minichromosome maintenance complex component 2
  • Zebrafish(192338) MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified, ,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Rabbit anti-MCM2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-MCM2 antibody, Rabbit monoclonal, clone SP85, recombinant, expressed in proprietary host, affinity isolated antibody,
Reactividad de especies
bovine, dog, frog, human, mouse, rat
Aplicación
flow cytometry
immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MCM2,
Especie
human
MISSION® esiRNA, targeting mouse Mcm2,
Especie
mouse