Saltar al contenido
Merck

MARCH8

membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase

Sinónimos:
MARCH-VIII, MIR, RNF178, c-MIR
Especie:
Human MARCH8 (220972), Mouse March8 (71779), Rat March8 (312656), sheep MARCH8 (101120136), naked mole-rat March8 (101701304), Zebrafish march8 (567818), domestic cat MARCH8 (101097021), chicken MARCH8 (423770), Horse MARCH8 (100062110), domestic guinea pig March8 (100718377) ...Más
ID UniProtKB:
Q5T0T0, B2R8E7, Q5T0S8, Q8TC72
ID del gen:
  • Human(220972) Summary: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]
  • Mouse(71779) membrane-associated ring finger (C3HC4) 8
  • Rat(312656) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
  • sheep(101120136) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
  • naked mole-rat(101701304) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
  • Zebrafish(567818) membrane-associated ring finger (C3HC4) 8
  • domestic cat(101097021) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
  • chicken(423770) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
  • Horse(100062110) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
  • domestic guinea pig(100718377) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
  • dog(606989) membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
  • cow(540667) membrane-associated ring finger (C3HC4) 8

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA014597
Anti-MARCH8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
EMU084291
MISSION® esiRNA, targeting mouse March8,
Especie
mouse
EHU007521
MISSION® esiRNA, targeting human MARCH8,
Especie
human