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Merck

MAPK9

mitogen-activated protein kinase 9

Sinónimos:
JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK
Especie:
ID UniProtKB:
ID del gen:
  • Human(5601) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
  • Mouse(26420) mitogen-activated protein kinase 9
  • Rat(50658) mitogen-activated protein kinase 9
  • Zebrafish(100149273) mitogen-activated protein kinase 9
  • chicken(395983) mitogen-activated protein kinase 9
  • cow(534125) mitogen-activated protein kinase 9
  • domestic cat(101084765) mitogen-activated protein kinase 9
  • Horse(100057961) mitogen-activated protein kinase 9
  • dog(474652) mitogen-activated protein kinase 9
  • Domestic Rabbit(100342664) mitogen-activated protein kinase 9
  • sheep(101120826) mitogen-activated protein kinase 9
  • domestic guinea pig(100714249) mitogen-activated protein kinase 9
  • naked mole-rat(101698286) mitogen-activated protein kinase 9

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-JNK2 Antibody, clone 1F16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, human, mouse
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-phospho-MAPK9 (pThr183) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-MAPK9 antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-SAPK antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Anti-Mapk9 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
SP600125, ≥98% (HPLC),
Especie
human
Adenina, ≥99%,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for cell culture,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for plant cell culture, ≥99%,
Especie
human, rat, mouse
α-Sexithiophene, ,
Especie
human, rat

Proteins

Referencia del producto
Descripción
Especie
JNK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MAPK9,
Especie
human
MISSION® esiRNA, targeting mouse Mapk9,
Especie
mouse