KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
Sinónimos:
HBK5, HK4, HUKIV, KV1.2, MK2, NGK1, RBK2
Especie:
Human KCNA2 (3737), Mouse Kcna2 (16490), Rat Kcna2 (25468), cow KCNA2 (539608), domestic cat KCNA2 (101083868), dog KCNA2 (404022), Zebrafish kcna2 (100537815), chicken KCNA2 (395117), naked mole-rat Kcna2 (101717332), domestic guinea pig Kcna2 (100735605)
ID UniProtKB:
ID del gen:
- Human(3737) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008]
- Mouse(16490) potassium voltage-gated channel, shaker-related subfamily, member 2
- Rat(25468) potassium voltage-gated channel, shaker-related subfamily, member 2
- cow(539608) potassium voltage-gated channel, shaker-related subfamily, member 2
- domestic cat(101083868) potassium voltage-gated channel, shaker-related subfamily, member 2
- dog(404022) potassium voltage-gated channel, shaker-related subfamily, member 2
- Zebrafish(100537815) potassium voltage-gated channel, shaker-related subfamily, member 2
- chicken(395117) potassium voltage-gated channel, shaker-related subfamily, member 2
- naked mole-rat(101717332) potassium voltage-gated channel, shaker-related subfamily, member 2
- domestic guinea pig(100735605) potassium voltage-gated channel, shaker-related subfamily, member 2
- sheep(101112012) potassium voltage-gated channel, shaker-related subfamily, member 2
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Antibodies
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Aplicación
Monoclonal Anti-KCNA2 antibody produced in mouse, clone S14-16, 1 mg/mL, purified immunoglobulin,
Reactividad de especies
human, mouse, rat, zebrafish
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Blocker
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