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Merck

IL5RA

interleukin 5 receptor, alpha

Sinónimos:
CD125, CDw125, HSIL5R3, IL5R
Especie:
ID UniProtKB:
ID del gen:
  • Human(3568) Summary: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]
  • Mouse(16192) interleukin 5 receptor, alpha
  • Rat(114103) interleukin 5 receptor, alpha
  • chicken(771801) interleukin 5 receptor, alpha
  • dog(476553) interleukin 5 receptor, alpha
  • domestic cat(101099031) interleukin 5 receptor, alpha
  • naked mole-rat(101701153) interleukin 5 receptor, alpha
  • sheep(101111837) interleukin 5 receptor, alpha
  • domestic guinea pig(100379257) interleukin 5 receptor, alpha
  • cow(615848) interleukin 5 receptor, alpha

Custom & Knockdown Gene Products

ELISA

Número de producto
Descripción
Especie
Human IL-5 R α ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human IL5RA,
Especie
human