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Merck

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Sinónimos:
5-HT2A, HTR2
Especie:
Human HTR2A (3356), Mouse Htr2a (15558), Rat Htr2a (29595), dog HTR2A (403882), naked mole-rat Htr2a (101708395), Horse HTR2A (100009685), chicken HTR2A (428070), domestic guinea pig Htr2a (100135545), domestic cat HTR2A (101081108), cow HTR2A (407230)
ID UniProtKB:
P28223, B2RAC5, B4DZ79, F5GWE8, Q5T8C0
ID del gen:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
M110
α-Methylserotonin maleate salt, ≥98% (HPLC),
Especie
human
M2525
Mianserin hydrochloride, ,
Especie
human
C117
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Especie
human, rat
F112
(+)-Fenfluramine hydrochloride, ,
Especie
human
Q1004
Quipazine maleate salt, ,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
D9190
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
M3324
M100907, ≥98% (HPLC),
Especie
human
D206709
2,2-Diphenylethylamine, 96%,
Especie
rat
S7201
SR-46349 hemifumarate salt, ≥98% (HPLC),
Especie
human
H0100000
Haloperidol, European Pharmacopoeia (EP) Reference Standard,
Especie
human
BP407
Haloperidol, British Pharmacopoeia (BP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB4301791
Anti-HTR2A, affinity isolated antibody,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot
SAB4501474
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
M2525
Mianserin hydrochloride, ,
Especie
human
Z101
Zimelidine dihydrochloride, solid,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
BP591
Trazodone hydrochloride impurity standard, British Pharmacopoeia (BP) Reference Standard,
Especie
human
BP590
Trazodone hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human
N5536
Nefazodone hydrochloride, ≥98% (HPLC), solid,
Especie
human
1457902
Nefazodone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
M8046
Mifepristone, ≥98%,
Especie
human, mouse, rat

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
H9772
5-Hydroxy-L-tryptophan, powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU023531
MISSION® esiRNA, targeting mouse Htr2a,
Especie
mouse