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Merck

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Sinónimos:
5-HT2A, HTR2
Especie:
Human HTR2A (3356), Mouse Htr2a (15558), Rat Htr2a (29595), dog HTR2A (403882), naked mole-rat Htr2a (101708395), Horse HTR2A (100009685), chicken HTR2A (428070), domestic guinea pig Htr2a (100135545), domestic cat HTR2A (101081108), cow HTR2A (407230)
ID UniProtKB:
P28223, B2RAC5, B4DZ79, F5GWE8, Q5T8C0
ID del gen:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

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Small Molecule - Agonist

Número de producto
Descripción
Especie
M110
α-Methylserotonin maleate salt, ≥98% (HPLC),
Especie
human
M2525
Mianserin hydrochloride, ,
Especie
human
C117
5-Carboxamidotryptamine maleate salt, powder, ≥98% (HPLC),
Especie
human, rat
F112
(+)-Fenfluramine hydrochloride, ,
Especie
human
Q1004
Quipazine maleate salt, ,
Especie
human

Small Molecule - Allosteric Modulator

Número de producto
Descripción
Especie
D9190
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Número de producto
Descripción
Especie
M3324
M100907, ≥98% (HPLC),
Especie
human
D206709
2,2-Diphenylethylamine, 96%,
Especie
rat
H0100000
Haloperidol, European Pharmacopoeia (EP) Reference Standard,
Especie
human
BP407
Haloperidol, British Pharmacopoeia (BP) Reference Standard,
Especie
human
S7201
SR-46349 hemifumarate salt, ≥98% (HPLC),
Especie
human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
SAB4501474
Anti-5-HT-2A antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
immunohistochemistry
SAB4301791
Anti-HTR2A, affinity isolated antibody,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Blocker

Número de producto
Descripción
Especie
M2525
Mianserin hydrochloride, ,
Especie
human

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
BP591
Trazodone hydrochloride impurity standard, British Pharmacopoeia (BP) Reference Standard,
Especie
human
N5536
Nefazodone hydrochloride, ≥98% (HPLC), solid,
Especie
human
1457902
Nefazodone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Especie
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Especie
human

Small Molecule - Ligand

Número de producto
Descripción
Especie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Número de producto
Descripción
Especie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Mixed Agonist/Antagonist

Número de producto
Descripción
Especie
M8046
Mifepristone, ≥98%,
Especie
human, mouse, rat

Small Molecule - Precursor

Número de producto
Descripción
Especie
H9772
5-Hydroxy-L-tryptophan, powder,
Especie
human

esiRNA

Número de producto
Descripción
Especie
EMU023531
MISSION® esiRNA, targeting mouse Htr2a,
Especie
mouse