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Merck

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

Sinónimos:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
Especie:
Human HTR1B (3351), Mouse Htr1b (15551), Rat Htr1b (25075), chicken HTR1B (421858), Zebrafish htr1b (561647), dog HTR1B (403741), cow HTR1B (317707), Horse HTR1B (100009680), domestic cat HTR1B (100144391), Domestic Rabbit HTR1B (100009594) ...Más
ID UniProtKB:
P28222, Q4VAY7
ID del gen:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
S1198
Sumatriptan succinate, ≥98% (HPLC), solid,
Especie
human
SML0248
Zolmitriptan, ≥98% (HPLC),
Especie
human
1457469
Naratriptan hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
1286413
Frovatriptan succinate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
1642201
Sumatriptan succinate, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
D9190
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
G5793
GR 127935 hydrochloride hydrate, >98% (HPLC), powder,
Especie
human
M149
Methiothepin mesylate salt, ≥98% (HPLC), solid,
Especie
human
P8688
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Especie
human
M137
Methysergide maleate salt, solid,
Especie
human
M3668
Metergoline, ,
Especie
human, rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA028808
Anti-HTR1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
SAB4501470
Anti-5-HT-1B antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry
SAB4501471
Anti-HTR1B antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
P8688
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Especie
human
Z101
Zimelidine dihydrochloride, solid,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Especie
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Especie
human
F132
Fluoxetina hydrochloride, solid,
Especie
human
R0875
Reserpine, ,
Especie
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
H9772
5-Hydroxy-L-tryptophan, powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU044151
MISSION® esiRNA, targeting mouse Htr1b,
Especie
mouse