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Merck

HTR1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

Sinónimos:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
Especie:
Human HTR1A (3350), Mouse Htr1a (15550), Rat Htr1a (24473), chicken HTR1A (431581), naked mole-rat Htr1a (101718872), dog HTR1A (487230), domestic guinea pig Htr1a (100301563), cow HTR1A (407137), Horse HTR1A (100009683), domestic cat HTR1A (101101542) ...Más
ID UniProtKB:
P08908, Q6LAE7
ID del gen:
  • Human(3350) Summary: This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
  • Mouse(15550) 5-hydroxytryptamine (serotonin) receptor 1A
  • Rat(24473) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • chicken(431581) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • naked mole-rat(101718872) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • dog(487230) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic guinea pig(100301563) 5-hydroxytryptamine (serotonin) receptor 1A
  • cow(407137) 5-hydroxytryptamine (serotonin) receptor 1A
  • Horse(100009683) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic cat(101101542) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • Domestic Rabbit(100008780) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • sheep(101105852) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
H140
(R)-(+)-8-Hydroxy-DPAT hydrobromide, ≥98% (HPLC), solid,
Especie
human
X4879
Xaliproden, ≥97% (HPLC), solid,
Especie
human
Y0000471
Buspirone for system suitability, European Pharmacopoeia (EP) Reference Standard,
Especie
human
SML1098
Vilazodone hydrochloride, ≥98% (HPLC),
Especie
human
B134
BMY 7378 dihydrochloride, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
D9190
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
125180
1-(3-Chlorophenyl)piperazine hydrochloride, 99%,
Especie
rat
W108
WAY-100635 maleate salt, powder,
Especie
human
471682
1-(3-Methoxyphenyl)piperazine, 95%,
Especie
rat
G0544
GR 103691, ≥98% (HPLC), solid,
Especie
rat
571415
1-(4-Methoxyphenyl)piperazine, 97%,
Especie
mouse, rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB4501469
Anti-5-HT-1A antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
HPA018073
Anti-HTR1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
P8688
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Especie
human
Z101
Zimelidine dihydrochloride, solid,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
SML1098
Vilazodone hydrochloride, ≥98% (HPLC),
Especie
human
V-076
Vilazodone hydrochloride solution, 1 mg/mL (Methanol:DMSO (90:10) (v/v)), certified reference material, ampule of 1 mL, Cerilliant®,
Especie
human
T13005
1,2,3,4-Tetrahydroisoquinoline, 95%,
Especie
rat, human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Especie
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Especie
human

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
B9308
BP897, >98% (HPLC), solid,
Especie
human, rat
M8046
Mifepristone, ≥98%,
Especie
human, mouse, rat

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
H9772
5-Hydroxy-L-tryptophan, powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU118601
MISSION® esiRNA, targeting human HTR1A,
Especie
human