HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
Sinónimos:
DFNB39, F-TCF, HGFB, HPTA, SF
Especie:
Human HGF (3082), Mouse Hgf (15234), Rat Hgf (24446), cow HGF (282879), sheep HGF (443075), Domestic Rabbit HGF (100316908), domestic guinea pig Hgf (100730730), naked mole-rat Hgf (101707056), chicken HGF (395941), dog HGF (403441)
ID UniProtKB:
ID del gen:
- Human(3082) Summary: Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(15234) hepatocyte growth factor
- Rat(24446) hepatocyte growth factor
- cow(282879) hepatocyte growth factor (hepapoietin A; scatter factor)
- sheep(443075) hepatocyte growth factor (hepapoietin A; scatter factor)
- Domestic Rabbit(100316908) hepatocyte growth factor (hepapoietin A; scatter factor)
- domestic guinea pig(100730730) hepatocyte growth factor (hepapoietin A; scatter factor)
- naked mole-rat(101707056) hepatocyte growth factor (hepapoietin A; scatter factor)
- chicken(395941) hepatocyte growth factor (hepapoietin A; scatter factor)
- dog(403441) hepatocyte growth factor (hepapoietin A; scatter factor)
- domestic cat(493705) hepatocyte growth factor (hepapoietin A; scatter factor)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-Hepatocyte Growth Factor antibody produced in mouse, clone 24612.111, purified immunoglobulin, lyophilized powder,
Reactividad de especies
human
Aplicación
ELISA
neutralization
western blot
neutralization
western blot
Anti-HGF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-Hepatocyte Growth Factor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-HGF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Proteins
Referencia del producto
Descripción
Especie
Hepatocyte Growth Factor human, HGF, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
Especie
human
Hepatocyte Growth Factor human, HGF, recombinant, expressed in NSO cells, suitable for cell culture,
Especie
human
Hepatocyte Growth Factor human, HGF, recombinant, expressed in Baculovirus infected High-5 cells, suitable for cell culture,
Especie
human
HGF mouse, recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE), ≥95% (HPLC),
Especie
mouse