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Merck

GUCA2B

guanylate cyclase activator 2B (uroguanylin)

Sinónimos:
GCAP-II, UGN
Especie:
ID UniProtKB:
ID del gen:
  • Human(2981) Summary: This gene encodes a member of the guanylin family, and is expressed in the stomach and intestine. This protein functions as an endogenous ligand for the guanylate cyclase-C receptor and stimulates an increase in cyclic GMP, a key component of several intracellular signal transduction pathways. It maybe involved in salt and water secretion into the intestinal lumen as well as the renal tubules, and thus regulate electrolyte homeostasis in these tissues. [provided by RefSeq, Oct 2011]
  • Mouse(14916) guanylate cyclase activator 2b (retina)
  • Rat(64055) guanylate cyclase activator 2B
  • dog(100684829) guanylate cyclase activator 2B (uroguanylin)
  • naked mole-rat(101720311) guanylate cyclase activator 2B (uroguanylin)
  • domestic guinea pig(100135535) guanylate cyclase activator 2b (retina)
  • domestic cat(101092381) guanylate cyclase activator 2B (uroguanylin)
  • Zebrafish(325935) guanylate cyclase activator 2B (uroguanylin)
  • cow(515664) guanylate cyclase activator 2B (uroguanylin)

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Kynurenic acid, ≥98%,
Especie
rat, human

Proteins

Referencia del producto
Descripción
Especie
Uroguanylin, ≥90% (HPLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GUCA2B,
Especie
human