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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Sinónimos:
EPND, GluN2A, NMDAR2A, NR2A
Especie:
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265), dog GRIN2A (490012), chicken GRIN2A (427678), domestic cat GRIN2A (101086110)
ID UniProtKB:
Q12879, O00669, Q17RZ6
ID del gen:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Número de producto
Descripción
Especie
239488
1,4-Bis(3-aminopropyl)piperazine, ≥95%,
Especie
rat
PHR1018
Dextromethorphan HBr, certified reference material,
Especie
human
1181007
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Especie
human
D9684
Dextromethorphan hydrobromide, meets USP testing specifications,
Especie
human
R1276
Reversin 121, ≥97% (HPLC), powder,
Especie
mouse, rat, human

Small Molecule - Allosteric Modulator

Número de producto
Descripción
Especie
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
Especie
human
1000554
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Especie
human
BP1172
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Especie
human
A78403
4-Aminopyridine, 98%,
Especie
rat, human, mouse
275875
4-Aminopyridine, ≥99%,
Especie
rat, human, mouse

Small Molecule - Antagonist

Número de producto
Descripción
Especie
P8791
Polyglycine, mol wt 500-5,000,
Especie
rat
S3256
Spermine, ≥97%,
Especie
rat, human
PHR1018
Dextromethorphan HBr, certified reference material,
Especie
human
S4264
Spermine, suitable for cell culture, BioReagent,
Especie
rat, human
P63204
2,3-Pyridinedicarboxylic acid, 99%,
Especie
rat

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
SAB5200888
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot
SAB5200978
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
SAB5200988
Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
SAB5200898
Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse, clone S327-95, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunohistochemistry
western blot
SAB4501304
Anti-NMDAR2A antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

Número de producto
Descripción
Especie
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Especie
human
K3375
Kynurenic acid, ≥98%,
Especie
rat, human
A78403
4-Aminopyridine, 98%,
Especie
rat, human, mouse
275875
4-Aminopyridine, ≥99%,
Especie
rat, human, mouse

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
I5109
Indole-2-carboxylic acid, 98%,
Especie
rat, human
D207756
1,3-Diphenylguanidine, 97%,
Especie
rat, mouse, human
N5501
Nω-Nitro-L-arginine, ≥98% (TLC),
Especie
rat, mouse, human
P0547
Pentamidine isethionate salt, powder,
Especie
human
324817
(Aminomethyl)phosphonic acid, 99%,
Especie
rat, human

Small Molecule - Mixed Agonist/Antagonist

Número de producto
Descripción
Especie
D18609
1,3-Diamino-2-propanol, 95%,
Especie
rat
115738
4-Amino-2,2,6,6-tetramethylpiperidine, 98%,
Especie
rat
33262
1,3-Diamino-2-propanol, purum, ≥96.5% (GC),
Especie
rat
534498
4-Piperidinopiperidine, 97%,
Especie
rat
65690
3-(Methylamino)propylamine, technical, ≥97.0% (GC),
Especie
rat

esiRNA

Número de producto
Descripción
Especie
EHU040271
MISSION® esiRNA, targeting human GRIN2A,
Especie
human
EMU051581
MISSION® esiRNA, targeting mouse Grin2a,
Especie
mouse