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Merck

GRAP

GRB2-related adaptor protein

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(10750) Summary: This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012]
  • Mouse(71520) GRB2-related adaptor protein
  • Rat(363616) GRB2-related adaptor protein
  • chicken(416523) GRB2-related adaptor protein
  • domestic cat(101085758) GRB2-related adaptor protein
  • dog(489534) GRB2-related adaptor protein
  • fruit fly(45433) grape
  • naked mole-rat(101721246) GRB2-related adaptor protein
  • cow(534491) GRB2-related adaptor protein
  • domestic guinea pig(100727005) GRB2-related adaptor protein
  • sheep(101110605) GRB2-related adaptor protein

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GRAP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-GRAP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-GRAP antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot

Proteins

Referencia del producto
Descripción
Especie
PrEST Antigen GRAP, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GRAP,
Especie
human
MISSION® esiRNA, targeting mouse Grap,
Especie
mouse