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Merck

GLE1

GLE1 RNA export mediator

Sinónimos:
GLE1L, LCCS, LCCS1, hGLE1
Especie:
ID UniProtKB:
ID del gen:
  • Human(2733) Summary: This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(74412) GLE1 RNA export mediator (yeast)
  • Rat(362098) GLE1 RNA export mediator
  • sheep(101119123) GLE1 RNA export mediator homolog (yeast)
  • Horse(100066964) GLE1 RNA export mediator homolog (yeast)
  • domestic guinea pig(100732111) GLE1 RNA export mediator
  • naked mole-rat(101722063) GLE1 RNA export mediator homolog (yeast)
  • cow(540982) GLE1 RNA export mediator homolog (yeast)
  • chicken(417212) GLE1 RNA export mediator
  • Zebrafish(445408) GLE1 RNA export mediator homolog (yeast)
  • dog(480704) GLE1 RNA export mediator homolog (yeast)
  • domestic cat(101080492) GLE1 RNA export mediator homolog (yeast)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GLE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-GLE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-GLE1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
horse, human, rat
Aplicación
western blot
Anti-GLE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-GLE1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GLE1,
Especie
human
MISSION® esiRNA, targeting mouse Gle1,
Especie
mouse