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Merck

GCLM

glutamate-cysteine ligase, modifier subunit

Sinónimos:
GLCLR
Especie:
ID UniProtKB:
ID del gen:
  • Human(2730) Summary: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008]
  • Mouse(14630) glutamate-cysteine ligase, modifier subunit
  • Rat(29739) glutamate cysteine ligase, modifier subunit
  • dog(612283) glutamate-cysteine ligase, modifier subunit
  • domestic guinea pig(100725164) glutamate-cysteine ligase, modifier subunit
  • domestic cat(101081562) glutamate-cysteine ligase, modifier subunit
  • fruit fly(248194) Glutamate-cysteine ligase modifier subunit
  • chicken(424492) glutamate-cysteine ligase, modifier subunit
  • naked mole-rat(101703324) glutamate-cysteine ligase, modifier subunit
  • sheep(101117899) glutamate-cysteine ligase, modifier subunit
  • Zebrafish(333974) glutamate-cysteine ligase, modifier subunit
  • cow(525659) glutamate-cysteine ligase, modifier subunit

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-GCLM Antibody, clone 1D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, mouse
Aplicación
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-GCLM antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-GCLM antibody produced in rabbit, ,
Reactividad de especies
Aplicación
western blot
Anti-GCLM antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
L-Buthionine-sulfoximine, ≥97% (TLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GCLM,
Especie
human
MISSION® esiRNA, targeting mouse Gclm,
Especie
mouse