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Merck

ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2

Sinónimos:
ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2
Especie:
ID UniProtKB:
ID del gen:
  • Human(5168) Summary: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
  • Mouse(18606) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Rat(84050) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • dog(482026) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • chicken(420361) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Zebrafish(393575) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • naked mole-rat(101710936) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic guinea pig(100722506) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • cow(532663) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • sheep(101120171) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • domestic cat(101097620) ectonucleotide pyrophosphatase/phosphodiesterase 2
  • Horse(100057101) ectonucleotide pyrophosphatase/phosphodiesterase 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ENPP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-ENPP2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
western blot

Proteins

Referencia del producto
Descripción
Especie
ENPP2, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ENPP2,
Especie
human
MISSION® esiRNA, targeting mouse Enpp2,
Especie
mouse