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Merck

DUSP11

dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)

Sinónimos:
PIR1
Especie:
ID UniProtKB:
ID del gen:
  • Human(8446) Summary: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. [provided by RefSeq, Sep 2008]
  • Mouse(72102) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • Rat(297412) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • sheep(101113742) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • chicken(423818) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • domestic cat(101098861) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • cow(508944) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • dog(483110) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • Zebrafish(550417) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • domestic guinea pig(100713554) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • naked mole-rat(101713434) dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DUSP11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human DUSP11,
Especie
human
MISSION® esiRNA, targeting mouse Dusp11,
Especie
mouse