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DRD1

dopamine receptor D1

Sinónimos:

DADR, DRD1A

Especie:

Human DRD1 (1812), Rat Drd1 (24316), Thale Cress DRD1 (816136), dog DRD1 (489110), domestic guinea pig Drd1 (100729180), naked mole-rat Drd1 (101720342), cow DRD1 (281125), sheep DRD1 (100568292), domestic cat DRD1 (101085098), Horse DRD1 (100058846)

ID UniProtKB:

P21728, B2RA44, Q4QRJ0

ID del gen:

Human(1812) Summary: This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
Rat(24316) dopamine receptor D1
Thale Cress(816136) putative chromatin remodeling protein
dog(489110) dopamine receptor D1
domestic guinea pig(100729180) dopamine receptor D1
naked mole-rat(101720342) dopamine receptor D1
cow(281125) dopamine receptor D1
sheep(100568292) dopamine receptor D1
domestic cat(101085098) dopamine receptor D1
Horse(100058846) dopamine receptor D1
chicken(427633) dopamine receptor D1

Productos (43)
Artículos con revisión científica externa. (207)

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Small Molecule - Agonist

Referencia del producto

Descripción

Especie

D047

(±)-SKF-38393 hydrochloride, crystalline, ≥98% (HPLC),

Especie

human

Fenoldopam mesylate, ≥98% (HPLC),

Especie

human

C130

Chloro-APB hydrobromide, solid,

Especie

human

Fenoldopam mesylate, United States Pharmacopeia (USP) Reference Standard,

Especie

human

S143

(±)-6-Chloro-PB hydrobromide, ≥98% (HPLC), solid,

Especie

human

Small Molecule - Antagonist

Referencia del producto

Descripción

Especie

D054

R(+)-SCH-23390 hydrochloride, ≥98% (HPLC), solid,

Especie

human

Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,

Especie

human

Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,

Especie

human

Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,

Especie

human

F114

cis-(Z)-Flupenthixol dihydrochloride, ≥98% (HPLC), solid,

Especie

human

Antibodies

Referencia del producto

Descripción

Reactividad de especies

Aplicación

Anti-DRD1 antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,

Reactividad de especies

human

Aplicación

immunofluorescence
western blot

Anti-DRD1 antibody produced in rabbit, affinity isolated antibody,

Reactividad de especies

human, mouse, rat

Aplicación

ELISA
immunofluorescence
immunohistochemistry

Anti-Dopamine D1 receptor Antibody, clone 2L4 ZooMAb^® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,

Reactividad de especies

bovine, camel, feline, human, monkey, porcine, rat, sheep

Aplicación

affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

Anti-D₁ Dopamine Receptor antibody,Rat monoclonal, clone 1-1-F11 s.E6, purified from hybridoma cell culture,

Reactividad de especies

human, monkey, rat

Aplicación

immunocytochemistry
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto

Descripción

Especie

D052

GBR 12909 dihydrochloride, solid, ≥98% (HPLC),

Especie

human

Amoxapine, United States Pharmacopeia (USP) Reference Standard,

Especie

human

Amoxapine, Pharmaceutical Secondary Standard; Certified Reference Material,

Especie

human

I119

Indatraline hydrochloride, solid,

Especie

human

Harmaline, ≥95%,

Especie

human, rat

Small Molecule - Metabolite

Referencia del producto

Descripción

Especie

3-Hydroxy-4-methoxyphenethylamine hydrochloride, ,

Especie

human

Small Molecule - Precursor

Referencia del producto

Descripción

Especie

3,4-Dihidroxi-L-fenilalanina, ≥98% (TLC),

Especie

mouse, human, rat

3,4-Dihydroxy-DL-phenylalanine, ,

Especie

mouse, human, rat

esiRNA

Referencia del producto

Descripción

Especie

MISSION^® esiRNA, targeting human DRD1,

Especie

human