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Merck

DEFA6

defensin, alpha 6, Paneth cell-specific

Sinónimos:
DEF6, HD-6
Especie:
ID UniProtKB:
ID del gen:
  • Human(1671) Summary: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Jul 2008]
  • Mouse(13240) defensin, alpha, 6
  • Rat(613223) defensin alpha 6
  • Horse(100307029) defensin, alpha 6, Paneth cell-specific

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DEFA6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human DEFA6,
Especie
human