Saltar al contenido
Merck

DDC

dopa decarboxylase (aromatic L-amino acid decarboxylase)

Sinónimos:
AADC
Especie:
ID UniProtKB:
ID del gen:
  • Human(1644) Summary: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
  • Mouse(13195) dopa decarboxylase
  • Rat(24311) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Zebrafish(406651) dopa decarboxylase
  • fruit fly(35190) Dopa decarboxylase
  • chicken(420947) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • dog(606852) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic cat(101082989) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • cow(280762) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Horse(100052557) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • sheep(101106765) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • naked mole-rat(101697555) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic guinea pig(100135516) dopa decarboxylase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Referencia del producto
Descripción
Especie
Human Dopa Decarboxylase ELISA, for serum, plasma and cell culture supernatants,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-DDC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-DDC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2962, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Monoclonal Anti-DOPA Decarboxylase (DDC) antibody produced in mouse, clone DDC-109, ascites fluid,
Reactividad de especies
bovine, canine, guinea pig, human, monkey, rabbit, rat, sheep
Aplicación
ELISA
immunocytochemistry

immunoprecipitation (IP)

microarray

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Benserazide hydrochloride, ≥98% (HPLC), solid,
Especie
human
Carbidopa, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Benserazide for peak identification A, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Benserazide hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Carbidopa, British Pharmacopoeia (BP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Ddc,
Especie
mouse