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Merck

CXCR4

chemokine (C-X-C motif) receptor 4

Sinónimos:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Especie:
ID UniProtKB:
ID del gen:
  • Human(7852) Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(12767) chemokine (C-X-C motif) receptor 4
  • Rat(60628) chemokine (C-X-C motif) receptor 4
  • cow(281736) chemokine (C-X-C motif) receptor 4
  • domestic guinea pig(100731341) chemokine (C-X-C motif) receptor 4
  • dog(483900) chemokine (C-X-C motif) receptor 4
  • naked mole-rat(101699254) chemokine (C-X-C motif) receptor 4
  • sheep(443532) neuropeptide Y receptor type 3
  • chicken(395324) chemokine (C-X-C motif) receptor 4
  • Domestic Rabbit(100346189) chemokine (C-X-C motif) receptor 4
  • domestic cat(493676) chemokine (C-X-C motif) receptor 4

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CXCR4 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
ELISA
flow cytometry

immunocytochemistry

immunofluorescence

immunoprecipitation (IP)

western blot
Anti-CXCR4 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-CXCR4 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
Aplicación
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-CXCR4 Antibody, clone 2L2, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
affinity binding assay

immunocytochemistry

immunohistochemistry
Anti-CXCR4 (Fusin) (182-196) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Cxcr4,
Especie
mouse
MISSION® esiRNA, targeting human CXCR4,
Especie
human