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Merck

CNR1

cannabinoid receptor 1 (brain)

Sinónimos:
CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR
Especie:
ID UniProtKB:
ID del gen:
  • Human(1268) Summary: This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]
  • Mouse(12801) cannabinoid receptor 1 (brain)
  • Rat(25248) cannabinoid receptor 1 (brain)
  • Zebrafish(404209) cannabinoid receptor 1
  • Horse(100065681) cannabinoid receptor 1 (brain)
  • naked mole-rat(101697935) cannabinoid receptor 1 (brain)
  • domestic guinea pig(100169690) cannabinoid receptor 1 (brain)
  • cow(100299449) cannabinoid receptor 1 (brain)
  • sheep(101111639) cannabinoid receptor 1 (brain)
  • domestic cat(493926) cannabinoid receptor 1 (brain)
  • dog(481913) cannabinoid receptor 1 (brain)
  • chicken(428633) cannabinoid receptor 1 (brain)

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Arachidonylethanolamide, ≥97.0% (TLC), oil,
Especie
rat
(R)-(+)-WIN 55,212-2 mesylate salt, ≥98% (HPLC),
Especie
human
Arachidonyl-2′-chloroethylamide hydrate, ≥97% (HPLC), oil,
Especie
rat, mouse
L-Tiroxina, ≥98% (HPLC),
Especie
human, mouse, rat
L-Tiroxina, powder, BioReagent, suitable for cell culture,
Especie
human, mouse, rat

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Cannabidiol solution, ~10 mg/mL in ethanol, analytical standard, for drug analysis,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Rimonabant hydrochloride, ≥98% (HPLC),
Especie
human
Stearoyl ethanolamide, ≥98%, crystalline,
Especie
rat
AM281, ≥98% (HPLC),
Especie
rat
L-Thyroxine sodium salt pentahydrate, γ-irradiated, powder, BioXtra, suitable for cell culture,
Especie
mouse, rat
L-Thyroxine sodium salt pentahydrate, ≥98% (HPLC), powder,
Especie
mouse, rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CNR1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CNR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-Cannabinoid Receptor 1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunohistochemistry

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
Palmitoylethanolamide, ,
Especie
human, rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Cnr1,
Especie
mouse
MISSION® esiRNA, targeting human CNR1,
Especie
human