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Merck

CHRNA6

cholinergic receptor, nicotinic, alpha 6 (neuronal)

Sinónimos:
CHNRA6
Especie:
ID UniProtKB:
ID del gen:
  • Human(8973) Summary: This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]
  • Mouse(11440) cholinergic receptor, nicotinic, alpha polypeptide 6
  • Rat(81721) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • domestic cat(101098219) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • domestic guinea pig(100723150) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • sheep(101119532) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • Horse(100049908) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • chicken(396321) cholinergic receptor, nicotinic, alpha 6
  • Zebrafish(555747) cholinergic receptor, nicotinic, alpha 6
  • dog(482836) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • naked mole-rat(101712413) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • cow(539113) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • Domestic Rabbit(100355656) cholinergic receptor, nicotinic, alpha 6 (neuronal)

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Decamethonium bromide, crystalline,
Especie
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Especie
human, rat

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Mecamylamine hydrochloride, ,
Especie
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Especie
human, rat
Kynurenic acid, ≥98%,
Especie
rat, human

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Tetraethylammonium chloride, ≥98% (titration),
Especie
human
Hexamethonium bromide, ,
Especie
human
Hexamethonium chloride, solid (hygroscopic),
Especie
human
Kynurenic acid, ≥98%,
Especie
rat, human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CHRNA6,
Especie
human