CELA3B
chymotrypsin-like elastase family, member 3B
Sinónimos:
CBPP, E1, EL-1, ELA3B
Especie:
Human CELA3B (23436), Mouse Cela3b (67868), Rat Cela3b (298567), domestic cat CELA3B (101094275), dog CELA3B (478196), naked mole-rat Cela3b (101701010), domestic guinea pig Cela3b (100717936), cow CELA3B (281752)
ID UniProtKB:
ID del gen:
- Human(23436) Summary: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays. [provided by RefSeq, May 2009]
- Mouse(67868) chymotrypsin-like elastase family, member 3B
- Rat(298567) chymotrypsin-like elastase family, member 3B
- domestic cat(101094275) chymotrypsin-like elastase family, member 3B
- dog(478196) chymotrypsin-like elastase family, member 3B
- naked mole-rat(101701010) chymotrypsin-like elastase family, member 3B
- domestic guinea pig(100717936) chymotrypsin-like elastase family, member 3B
- cow(281752) chymotrypsin-like elastase family, member 3B
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