Saltar al contenido
Merck

CASR

calcium-sensing receptor

Sinónimos:
CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, HYPOC1, NSHPT, PCAR1
Especie:
ID UniProtKB:
ID del gen:
  • Human(846) Summary: The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008]
  • Mouse(12374) calcium-sensing receptor
  • Rat(24247) calcium-sensing receptor
  • naked mole-rat(101725174) calcium-sensing receptor
  • domestic guinea pig(100718111) calcium-sensing receptor
  • cow(281038) calcium-sensing receptor
  • chicken(418266) calcium-sensing receptor
  • dog(488007) calcium-sensing receptor
  • domestic cat(100302732) calcium-sensing receptor
  • Horse(100034084) calcium-sensing receptor
  • sheep(101112527) calcium-sensing receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CASR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-CASR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-Calcium Sensing Receptor antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Monoclonal Anti-Calcium Sensing Receptor from mouse, clone HL1499 (6D4-3F4-6C4), purified from hybridoma cell culture,
Reactividad de especies
human, mouse, rabbit, rat
Aplicación
ELISA
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CASR,
Especie
human