CASP4
caspase 4, apoptosis-related cysteine peptidase
Sinónimos:
ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX
Especie:
Human CASP4 (837), Mouse Casp4 (12363), Rat Casp4 (114555), dog CASP4 (403724), naked mole-rat Casp4 (101700797), domestic guinea pig Casp4 (100731032), cow CASP4 (338039)
ID UniProtKB:
ID del gen:
- Human(837) Summary: This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Mouse(12363) caspase 4, apoptosis-related cysteine peptidase
- Rat(114555) caspase 4, apoptosis-related cysteine peptidase
- dog(403724) caspase 4, apoptosis-related cysteine peptidase
- naked mole-rat(101700797) caspase 4, apoptosis-related cysteine peptidase
- domestic guinea pig(100731032) caspase 4, apoptosis-related cysteine peptidase
- cow(338039) caspase 4, apoptosis-related cysteine peptidase
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-Caspase 11 antibody produced in rat, clone 17D9, purified from hybridoma cell culture,
Reactividad de especies
mouse
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CASP4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Caspase-4 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Caspase-13 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Referencia del producto
Descripción
Especie
esiRNA
Small Molecule - Substrate
Referencia del producto
Descripción
Especie
N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder,
Especie
rat, mouse, human