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Merck

CACNA1B

calcium channel, voltage-dependent, N type, alpha 1B subunit

Sinónimos:
BIII, CACNL1A5, CACNN, Cav2.2
Especie:
ID UniProtKB:
ID del gen:
  • Human(774) Summary: The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(12287) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Rat(257648) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • cow(282410) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • chicken(374169) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • dog(480660) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • Domestic Rabbit(100008979) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • naked mole-rat(101697609) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • domestic guinea pig(100735203) calcium channel, voltage-dependent, N type, alpha 1B subunit
  • domestic cat(101087362) calcium channel, voltage-dependent, N type, alpha 1B subunit

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Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Levetiracetam, ≥98% (HPLC),
Especie
human
Levetiracetam, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Levetiracetam, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Levetiracetam, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CACNA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-CACNA1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-Calcium Channel (α1B Subunit) (N-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
mouse, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Levetiracetam, ≥98% (HPLC),
Especie
human
Levetiracetam, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Levetiracetam, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Levetiracetam, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Bepridil hydrochloride, powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Cacna1b,
Especie
mouse
MISSION® esiRNA, targeting human CACNA1B,
Especie
human