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Merck

BCL2L1

BCL2-like 1

Sinónimos:
BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS
Especie:
ID UniProtKB:
ID del gen:
  • Human(598) Summary: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]
  • Mouse(12048) BCL2-like 1
  • Rat(24888) Bcl2-like 1
  • Domestic Rabbit(100008875) BCL2-like 1
  • domestic guinea pig(100730495) BCL2-like 1
  • Zebrafish(114401) bcl2-like 1
  • cow(282152) BCL2-like 1
  • domestic cat(493701) BCL2-like 1
  • chicken(373954) BCL2-like 1
  • dog(403618) BCL2-like 1
  • sheep(443061) BCL2-like 1
  • naked mole-rat(101713410) BCL2-like 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Bcl-xL Antibody, clone 1O8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, mouse, porcine, rat
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-BCL2L1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-BCL-XL antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Bcl-XL Antibody, clone 2V10G9, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot

Proteins

Referencia del producto
Descripción
Especie
Bcl-xL Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human BCL2L1,
Especie
human
MISSION® esiRNA, targeting mouse Bcl2l1,
Especie
mouse