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Merck

ATP1A3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

Sinónimos:
AHC2, DYT12, RDP
Especie:
ID UniProtKB:
ID del gen:
  • Human(478) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Mouse(232975) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Rat(24213) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic cat(101083636) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • Horse(100069796) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • dog(612463) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • chicken(396467) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • naked mole-rat(101721146) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • cow(282598) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • sheep(101103751) ATPase, Na+/K+ transporting, alpha 3 polypeptide
  • domestic guinea pig(100712985) ATPase, Na+/K+ transporting, alpha 3 polypeptide

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-ATP1A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-ATP1A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-Na+/K+ ATPase (α3 Subunit) antibody produced in mouse, 1 mg/mL, clone XVIF9-G10, ascites fluid,
Reactividad de especies
canine, guinea pig, human, monkey, rabbit, rat, sheep
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Digitoxin, ≥92% (HPLC), powder,
Especie
human
Digoxin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Digitoxin, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Digoxin, analytical standard,
Especie
human
Digoxin, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Atp1a3,
Especie
mouse
MISSION® esiRNA, targeting human ATP1A3,
Especie
human