APOE
apolipoprotein E
Sinónimos:
AD2, LDLCQ5, LPG
Especie:
Human APOE (348), Mouse Apoe (11816), Rat Apoe (25728), naked mole-rat Apoe (101717206), domestic guinea pig Apoe (100731633), cow APOE (281004), Domestic Rabbit APOE (100009337), dog APOE (476438), domestic cat APOE (101086769)
ID UniProtKB:
ID del gen:
- Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
- Mouse(11816) apolipoprotein E
- Rat(25728) apolipoprotein E
- naked mole-rat(101717206) apolipoprotein E
- domestic guinea pig(100731633) apolipoprotein E
- cow(281004) apolipoprotein E
- Domestic Rabbit(100009337) apolipoprotein E
- dog(476438) apolipoprotein E
- domestic cat(101086769) apolipoprotein E
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ELISA
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-APOE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APOE (C-terminal) antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-ApoE Antibody, clone 3N14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
flow cytometry
immunocytochemistry
Proteins
Referencia del producto
Descripción
Especie
Apolipoprotein E4 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder,
Especie
human
esiRNA
Referencia del producto
Descripción
Especie