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Merck

AKR1B1

aldo-keto reductase family 1, member B1 (aldose reductase)

Sinónimos:
ADR, ALDR1, ALR2, AR
Especie:
ID UniProtKB:
ID del gen:
  • Human(231) Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
  • Rat(24192) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Domestic Rabbit(100009122) aldo-keto reductase family 1, member B1 (aldose reductase)
  • naked mole-rat(101720124) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic guinea pig(100718017) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Zebrafish(415138) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic cat(101095406) aldo-keto reductase family 1, member B1 (aldose reductase)
  • cow(317748) aldo-keto reductase family 1, member B1 (aldose reductase)
  • dog(607537) aldo-keto reductase family 1, member B1 (aldose reductase)
  • sheep(101120824) aldo-keto reductase family 1, member B1 (aldose reductase)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Ácido (±) -6- hidroxi -2,5,7,8-tetrametilcromano-2- carboxílico, 97%,
Especie
rat
Hippuric acid, 98%,
Especie
rat
Fluorene-9-carboxylic acid, 96%,
Especie
rat
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human AKR1B1,
Especie
human