AIRE
autoimmune regulator
Sinónimos:
AIRE1, APECED, APS1, APSI, PGA1
Especie:
Human AIRE (326), Mouse Aire (11634), Rat Aire (294328), domestic guinea pig Aire (100729880), sheep AIRE (101102698), cow AIRE (784775), Zebrafish aire (100007662), chicken AIRE (429666), dog AIRE (487796), naked mole-rat Aire (101725873)
ID UniProtKB:
ID del gen:
- Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
- Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
- Rat(294328) autoimmune regulator
- domestic guinea pig(100729880) autoimmune regulator
- sheep(101102698) autoimmune regulator
- cow(784775) autoimmune regulator
- Zebrafish(100007662) autoimmune regulator
- chicken(429666) autoimmune regulator
- dog(487796) autoimmune regulator
- naked mole-rat(101725873) autoimmune regulator
- domestic cat(101091039) autoimmune regulator
Custom & Knockdown Gene Products
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-AIRE antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
western blot
western blot