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  • 2,2,2-trifluoroethyl formate: a versatile and selective reagent for the formylation of alcohols, amines, and N-hydroxylamines.

2,2,2-trifluoroethyl formate: a versatile and selective reagent for the formylation of alcohols, amines, and N-hydroxylamines.

Organic letters (2002-01-05)
David R Hill, Chi-Nung Hsiao, Ravi Kurukulasuriya, Steven J Wittenberger
ABSTRACT

[reaction: see text] Treatment of a variety of alcohols, amines, and N-hydroxylamines with 2,2,2-trifluoroethyl formate gave the corresponding formylated adducts in high yields.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
2,2,2-Trifluoroethyl formate, 95%