- gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride.
gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride.
Chemical communications (Cambridge, England) (2005-01-27)
V Prakash Reddy, Ramesh Alleti, Meher K Perambuduru, Urs Welz-Biermann, Herwig Buchholz, G K Surya Prakash
PMID15672167
ABSTRACT
2,2-diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent combination involving Selectfluor and pyridinium polyhydrogen fluoride (PPHF) under mild conditions in moderate to good yields.