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  • An Interactive Database for the Assessment of Histone Antibody Specificity.

An Interactive Database for the Assessment of Histone Antibody Specificity.

Molecular cell (2015-07-28)
Scott B Rothbart, Bradley M Dickson, Jesse R Raab, Adrian T Grzybowski, Krzysztof Krajewski, Angela H Guo, Erin K Shanle, Steven Z Josefowicz, Stephen M Fuchs, C David Allis, Terry R Magnuson, Alexander J Ruthenburg, Brian D Strahl
ABSTRACT

Access to high-quality antibodies is a necessity for the study of histones and their posttranslational modifications (PTMs). Here we debut the Histone Antibody Specificity Database (http://www.histoneantibodies.com), an online and expanding resource cataloging the behavior of widely used, commercially available histone antibodies by peptide microarray. This interactive web portal provides a critical resource to the biological research community that routinely uses these antibodies as detection reagents for a wide range of applications.