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Choosing the Optimal Cell Culture Media for Vaccine Production
Choosing the optimal cell culture media for vaccine production
Cost Modeling Vaccine Manufacturing: Estimate Production Costs for mRNA and other Vaccine Modalities
A custom-designed cost model is used to explore the economics of vaccine manufacturing across several different modalities including mRNA. The model enables greater process understanding, simulates bottlenecks, and helps to optimize production efficiency.
Virus-like Particle (VLP) Vaccine Bioprocessing and Formulation Steps
This technical article breaks down the steps of upstream and downstream bioprocessing and formulation of virus-like particle vaccines.
Virus-like Particles (VLPs) Vaccine Manufacturing
VLP vaccine manufacturers must optimize upstream productivity with reliable scale-up, achieve yield and efficiency goals with robust impurity removal, maximize downstream recovery, and ensure patient safety. Merck’s integrated portfolio, regulatory and applications expertise can help address these process challenges.
Plasmid DNA Purification Process
Free eBook outlines plasmid DNA manufacturing process and downstream purification challenges for various applications.
Vaccine Manufacturing
From early phase development, through downstream purification to large scale vaccine production: learn more about vaccine process development and application expertise.
mRNA Vaccines and Therapeutics Manufacturing
mRNA vaccine technology offers rapid development and scalable manufacturing for disease prevention.
Coronavirus (SARS-CoV-2) Viral Proteins
SARS-CoV-2 structural proteins: envelope (E), membrane (M), nucleocapsid (N), spike (S). Explore related reagents for research.
A Sensitive Method to Quantify HIV-1 Antibody in Mucosal Samples
A Sensitive Method to Quantify HIV-1 Antibody in Mucosal Samples
Personalized T cell therapy for HBV and HCC
This webinar explores challenges and strategies in T cell engineering for promising cancer immunotherapy options.
Choosing the optimal cell culture media for vaccine production
Choosing the optimal cell culture media for vaccine production
Platform Technologies to Accelerate Novel Vaccine Development and Manufacturing
In this webinar, we present a comparison of novel technologies, discuss key considerations for manufacturing, and share selected case studies for platforms such as virus-like-particles, viral vectors, plasmid DNA, and mRNA platforms.
Egg-based and Cell-based Influenza Vaccine Manufacturing Methods
Influenza vaccines are commonly made using egg-based and cell-based manufacturing strategies. Find step-by-step information on the manufacturing process for each method.
mRNA Synthesis for the Development of Vaccines and Therapeutics
Understand how mRNA vaccines induce immunity. and read how synthetic mRNA is prepared for vaccine immunogens and other biopharmaceuticals. Find reagents for synthesis of mRNA.
Cell Harvest, Lysis, Neutralization and Clarification of Plasmid DNA (pDNA) for mRNA, plasmid-based DNA Vaccines, and Viral Vector applications
An overview of the cell harvest, lysis, neutralization, and clarification steps used for pDNA purification along with case study and practical advice.
BIO International
We warmly invite you to visit booth 4735 at BIO International and connect with the MilliporeSigma team.
Virus-Based Vaccine Manufacturing
Tailored viral vaccine manufacturing addresses virus-specific challenges through collaboration.
Viral Vector Vaccine Mfg.
A templated process produces live vector vaccines. Challenges: yield loss, filtration, aggregation, scaling. Collaboration overcomes manufacturing hurdles.
Eshmuno® Fit Custom Affinity Resin Development Services: Frequently Asked Questions
This page answers all the frequently asked questions related to our Eshmuno® Fit custom affinity resin development services.
Bioprocessing Summit
Vaccine processing evolution focuses on agile manufacturing solutions amid the COVID pandemic.
Plasmid DNA Vaccines Manufacturing
Learn about overcoming challenges in manufacturing pDNA vaccines, including low productivity and separation issues.
Manufacturing Strategies for mRNA Vaccines and Therapeutics
mRNA technology offers therapeutic versatility; its delivery systems induce protein production for various applications.
Protein Subunit Vaccine Manufacturing
This page provides an overview of protein subunit vaccines, which incorporate a recombinant protein fragment derived from the viral pathogen. It includes a description of the subunit vaccine manufacturing workflow and the products and technologies that are essential to ensure