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EMU019891

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Rnf5

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AATGCCCATGAACCTTTCAGAAGAGGCGCAGGTGTGGATCTGGGACAGGGTCACCCAGCCTCCAGCTGGCAAGATTCCCTATTCCTGTTCCTCGCCATCTTTTTCTTTTTCTGGCTGCTCAGTATTTGAGCTCTGTCTCCTCCCTGCCCACCTCCAGCTAGAGGAGAATCAGTATTGGGAGTCCTGTGCTGGCCTTTCCTTGCTTTTGGACCACCCCCTTACTTCCATGACCCATCTCTGTCTGCTGAGGCCTCTCTCTTGGGAGGGCATGGCGAGGAGTGACCAGTCTGCTTAAGATGGGAGTGCCTGCTGCTGTGTACTGCTGGCCCAGTAGCACAGACACTGTCAGCCTGGAGGACGGACAGACAGACAGGTGTCCAGTTCTCCCAATCCTTTGCTTTCCCCCAGATTTCTTGATTTGGTGTTTAAAGGTGGGCTC

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Sridevi Yadavilli et al.
Oncotarget, 6(14), 12141-12155 (2015-05-20)
Diffuse intrinsic pontine gliomas (DIPGs) have a dismal prognosis and are poorly understood brain cancers. Receptor tyrosine kinases stabilized by neuron-glial antigen 2 (NG2) protein are known to induce gliomagenesis. Here, we investigated NG2 expression in a cohort of DIPG
Frank Maus et al.
PloS one, 10(9), e0137311-e0137311 (2015-09-05)
The NG2 proteoglycan is characteristically expressed by oligodendrocyte progenitor cells (OPC) and also by aggressive brain tumours highly resistant to chemo- and radiation therapy. Oligodendrocyte-lineage cells are particularly sensitive to stress resulting in cell death in white matter after hypoxic

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