TRPM5
transient receptor potential cation channel, subfamily M, member 5
Synonyms:
LTRPC5, MTR1
Species:
Human TRPM5 (29850), Mouse Trpm5 (56843), Rat Trpm5 (365391), Zebrafish trpm5 (557722), chicken TRPM5 (423091), naked mole-rat Trpm5 (101709030), domestic guinea pig Trpm5 (100720335), sheep TRPM5 (101119861), domestic cat TRPM5 (101092891), cow TRPM5 (100299596)
UniProtKB ID:
Gene ID:
- Human(29850) Summary: This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele. [provided by RefSeq, Oct 2010]
- Mouse(56843) transient receptor potential cation channel, subfamily M, member 5
- Rat(365391) transient receptor potential cation channel, subfamily M, member 5
- Zebrafish(557722) transient receptor potential cation channel, subfamily M, member 5
- chicken(423091) transient receptor potential cation channel, subfamily M, member 5
- naked mole-rat(101709030) transient receptor potential cation channel, subfamily M, member 5
- domestic guinea pig(100720335) transient receptor potential cation channel, subfamily M, member 5
- sheep(101119861) transient receptor potential cation channel, subfamily M, member 5
- domestic cat(101092891) transient receptor potential cation channel, subfamily M, member 5
- cow(100299596) transient receptor potential cation channel, subfamily M, member 5
- dog(483668) transient receptor potential cation channel, subfamily M, member 5
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