SLC6A4
solute carrier family 6 (neurotransmitter transporter), member 4
Synonyms:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
Species:
Human SLC6A4 (6532), Mouse Slc6a4 (15567), Rat Slc6a4 (25553), domestic guinea pig Slc6a4 (100135619), naked mole-rat Slc6a4 (101705584), Domestic Rabbit SLC6A4 (100340600), Domestic Rabbit SLC6A4 (100351801), dog SLC6A4 (491184), domestic cat SLC6A4 (101091163), Horse SLC6A4 (100053721) ...More
UniProtKB ID:
Gene ID:
- Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
- Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
- domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
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Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SLC6A4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-Serotonin transporter Antibody, clone 5T7M2, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Sertraline hydrochloride impurity standard, British Pharmacopoeia (BP) Reference Standard,
Species
human
Paroxetine hydrochloride hemihydrate, British Pharmacopoeia (BP) Reference Standard,
Species
human
esiRNA
Product Number
Description
Species