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Merck

RAPGEF2

Rap guanine nucleotide exchange factor (GEF) 2

Synonyms:
CNrasGEF, NRAPGEP, PDZ-GEF1, PDZGEF1, RA-GEF, Rap-GEP, nRap GEP
Species:
Human RAPGEF2 (9693), Mouse Rapgef2 (76089), Rat Rapgef2 (310533), domestic guinea pig Rapgef2 (100725060), naked mole-rat Rapgef2 (101718791), sheep RAPGEF2 (101111578), Domestic Rabbit RAPGEF2 (100346752), dog RAPGEF2 (482670), domestic cat RAPGEF2 (101084954), Horse RAPGEF2 (100069003) ...More
UniProtKB ID:
Q9Y4G8, D3DP27
Gene ID:
  • Human(9693) Summary: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]
  • Mouse(76089) Rap guanine nucleotide exchange factor (GEF) 2
  • Rat(310533) Rap guanine nucleotide exchange factor (GEF) 2
  • domestic guinea pig(100725060) Rap guanine nucleotide exchange factor (GEF) 2
  • naked mole-rat(101718791) Rap guanine nucleotide exchange factor (GEF) 2
  • sheep(101111578) Rap guanine nucleotide exchange factor (GEF) 2
  • Domestic Rabbit(100346752) Rap guanine nucleotide exchange factor (GEF) 2
  • dog(482670) Rap guanine nucleotide exchange factor (GEF) 2
  • domestic cat(101084954) Rap guanine nucleotide exchange factor (GEF) 2
  • Horse(100069003) Rap guanine nucleotide exchange factor (GEF) 2
  • cow(100139484) Rap guanine nucleotide exchange factor (GEF) 2
  • Zebrafish(557693) Rap guanine nucleotide exchange factor (GEF) 2
  • chicken(422418) Rap guanine nucleotide exchange factor (GEF) 2

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA068798
Anti-RAPGEF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
EMU059531
MISSION® esiRNA, targeting mouse Rapgef2,
Species
mouse
EHU043371
MISSION® esiRNA, targeting human RAPGEF2,
Species
human