PRNP
prion protein
Synonyms:
ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30
Species:
Human PRNP (5621), Mouse Prnp (19122), Rat Prnp (24686), domestic cat PRNP (493886), chicken PRNP (396452), Horse PRNP (100065904), naked mole-rat Prnp (101710391), cow PRNP (281427), domestic guinea pig Prnp (100714701), sheep PRNP (493887) ...More
UniProtKB ID:
Gene ID:
- Human(5621) Summary: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
- Mouse(19122) prion protein
- Rat(24686) prion protein
- domestic cat(493886) prion protein
- chicken(396452) prion protein
- Horse(100065904) prion protein
- naked mole-rat(101710391) prion protein
- cow(281427) prion protein
- domestic guinea pig(100714701) prion protein
- sheep(493887) prion protein
- Domestic Rabbit(100345744) prion protein
- dog(485783) prion protein
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Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Prion Protein Antibody, clone 3D0J9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-PRNP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-PRNP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-Prion Protein antibody, Mouse monoclonal, clone 8H4, purified from hybridoma cell culture,
Species Reactivity
bovine, human, monkey, mouse, rat, sheep
Application
ELISA
electron microscopy
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
electron microscopy
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Proteins
esiRNA
Product Number
Description
Species